A bone marrow transplant can be a life-saving treatment for many serious diseases. With better matching, improved medications, and supportive care, outcomes continue to get better.
Looking for trusted bone marrow transplant services? At Broad Health Network , we specialize in life-saving bone marrow and stem cell transplants for patients with blood cancers, bone marrow failure syndromes, and genetic blood disorders.
Our multidisciplinary team of transplant specialists offers both autologous and allogeneic bone marrow transplants, using the latest medical advancements to ensure the best possible outcomes.
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High-dose chemotherapy, radiation, or both are given to kill any cancer cells. This also kills all healthy bone marrow that remains, and allows new stem cells to grow in the bone marrow.
Lower doses of chemotherapy and radiation are given before a transplant. This allows older people, and those with other health problems to have a transplant.
The term auto means self. Stem cells are removed from you before you receive high-dose chemotherapy or radiation treatment. The stem cells are stored in a freezer. After high-dose chemotherapy or radiation treatments, your stem cells are put back in your body to make normal blood cells. This is called a rescue transplant.
This is a type of allogeneic transplant. Stem cells are removed from a newborn baby’s umbilical cord right after birth. The stem cells are frozen and stored until they are needed for a transplant. Umbilical cord blood cells are very immature so there is less of a need for perfect matching. Due to the smaller number of stem cells, blood counts take much longer to recover.
This minor surgery is done under general anesthesia. This means the donor will be asleep and pain-free during the procedure. The bone marrow is removed from the back of both hip bones. The amount of marrow removed depends on the weight of the person who is receiving it. This method is rarely performed today.
First, the donor is given several days of shots to help stem cells move from the bone marrow into the blood. During leukapheresis, blood is removed from the donor through an IV line. The part of white blood cells that contains stem cells is then separated in a machine and removed to be later given to the recipient. The red blood cells are returned to the donor.
A bone marrow transplant is a medical procedure used to replace damaged or diseased bone marrow with healthy stem cells. It’s often used to treat blood cancers and other serious bone marrow disorders.
Bone marrow transplant is used to treat:
Both methods involve stem cells, but they differ in how the cells are collected:
GVHD occurs when donor cells attack the recipient’s body. It’s a complication of allogeneic transplants and can affect the skin, liver, and digestive system. Medications can help manage it.
Success depends on:
Advancements in transplant techniques have improved survival rates significantly in recent years.
There are three main types of bone marrow transplants:
A donor match is determined using HLA (Human Leukocyte Antigen) typing, which compares proteins found on the surface of white blood cells. A close match is crucial to reduce the risk of rejection.
While often lifesaving, BMT carries risks such as:
Close monitoring is essential during recovery.
Recovery time varies but typically includes:
Donors can be:
Joining a donor registry can save lives.